PYP and HMDP Supply Issues Expected in Early 2026

ASNC has confirmed reports that supply disruptions with both Tc-99m pyrophosphate (PYP) and Tc-99m hydroxymethylene diphosphonate (HMDP or HDP) may take place after January 2026. These products are used in the diagnosis of cardiac amyloidosis.

ASNC is in contact with the manufacturers of both products to understand the extent of the shortages and the projected timelines for resuming production.

ASNC will share updates as this issue evolves. To be among the first to receive email alerts with breaking news, be sure to keep your ASNC membership current.

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