Masterclass in Cardiac Amyloidosis: Disease Spectrum, Diagnosis and Management

Join us March 7-9, 2025, for the virtual Masterclass in Cardiac Amyloidosis: Disease Spectrum, Diagnosis and Management.

This program is offered free of charge.

Led by Program Chair, Saurabh Malhotra, MD, MPH, FASNC, Masterclass features multidisciplinary content that today’s practitioners need to keep current in the rapidly advancing field of cardiac amyloidosis.

Masterclass will cover:

• the pathogenesis of cardiac amyloidosis;
• diagnostic techniques and pitfalls;
• management strategies;
• mechanisms to facilitate early diagnosis; and
• treatment and management.

The program will feature in-depth sessions led by expert cardiologists, multimodality imagers, hematologists, and neurologists to discuss the disease spectrum, diagnosis, and management of cardiac amyloidosis.

For Technologists: There will be a two-hour session, “Amyloidosis for Technologists: Tips and Tricks from Experts” on Saturday, March 8 from 1-3pm ET.

This session is essential for technologists who are or will be performing radionuclide imaging for cardiac amyloidosis. Leading experts will guide you through an overview of the disease, image acquisition and processing and recommendations to avoid potential pitfalls.

Register Now

Credits

Earn up to 11* CME/MOC credits.
2* CE credits for the technologist session, Amyloidosis for Technologists: Tips and Tricks from Experts.

Learning Objectives

By the end of the program, you should be able to:

• Describe amyloidosis, including specific types, cardiac features, and disease burden.
• Identify barriers to identification and diagnosis of patients suspected of ATTR.
• Summarize the diagnostic evaluation for cardiac amyloidosis including multimodality imaging and laboratory testing and identify prognostic markers.
• Recognize patients at risk for hereditary ATTR (hATTR) and wild-type ATTR (wtATTR).
• Explain the importance of genetic testing in hATTR.
• Discuss the therapeutic landscape and impact on disease burden.
• Define appropriate treatment and management strategies for patients with heart failure.
• Formulate strategies for development of a multidisciplinary care team.
• Evaluate potential community outreach activities to identify at-risk patients.

Agenda

Friday, March 7, 2025, 5:00 pm – 7:30 pm (US ET)

5:00 pm – Introduction, program goals and logistics
5:05 pm – #1. ASNC’s role in amyloidosis education
Session 1: Disease and Pathogenesis:
5:10 pm – #2. Amyloid fibrils and amyloidogenesis
5:40 pm – #3. Clinical manifestations of amyloidosis: moving the needle to early diagnosis
6:10 pm – #4. Polyneuropathy for the non-neurologists
6:40 pm – #5. Need for increasing awareness of musculoskeletal manifestations of amyloidosis
7:10 pm – Summary and closing comments

Saturday, March 8, 2025, 10:00 am – 3:30 pm

10:00 am – Introduction to Day 2
Session 2: Diagnostic Techniques and Pitfalls: A Case-Based Discussion
10:05 am – #6. Routine and advanced echocardiography techniques
10:35 am – #7. Cardiac magnetic resonance for diagnosis and disease management
11:05 am – #8. Nuclear scintigraphy with bone avid tracers: Basics and beyond
11:35 am – #9. Amyloid mutations and role of genetic testing
12:05 am – #10. Role of tissue diagnosis and challenges
12:35 pm – Final comments
12:35 pm – 1:00 pm – Break
Session 3: Challenges in Diagnosis and Management of ATTR
1:00 pm – #11. Amyloidosis in the community
1:45 pm – #12. Challenges with access to treatment
2:15 pm – #13. Challenges in underrepresented populations (age, ethnicity)
2:45 pm – Panel discussion: Everyday challenges
3:15 pm – Closing comments

Sunday, March 9, 2025, 10:00 am – 12:30 pm

10:00 am – Introduction to Day 3
Session 4: Practical Concepts for Treatment of Amyloidosis
10:00 am – #14. Application of prognostic markers in AL and ATTR amyloidosis
10:30 am – #15. Differentiating TTR from myeloma precursors
11:00 am – #16. How to determine choice of therapy: Is more better?
11:30 am – #17. Management of HF in amyloid patients
12:00 pm – Q&A
12:30 pm – Final comments and adjourn

*Credits subject to change

Amyloidosis for Technologists: Tips and Tricks from Experts

Overview

As part of this year’s Amyloidosis Masterclass (March 7-9 , 2025) ASNC will offer a focused 2-hour session for technologists titled, Amyloidosis for Technologists: Tips and Tricks from Experts on Saturday, March 8 from 1-3pm ET. This session is essential for technologists who are or will be performing radionuclide imaging for cardiac amyloidosis. This session will provide an overview of the disease, image acquisition and processing and recommendations to avoid potential pitfalls. Join us for an informative session with leading experts. The session will offer 2* CE credits for technologists.

Objectives

• Describe the importance of differentiating amyloid transthyretin cardiac amyloidosis from light-chain amyloidosis
• Compare technetium-99m (Tc-99m) HMDP and Tc-99m PYP for diagnosis of cardiac amyloidosis
• Summarize key parameters acquisition and processing of Tc-99m bone avid tracers with NaI and CZT camera systems.
• Identify artifacts and common pitfalls associated with Tc-99m bone avid tracers for detecting cardiac amyloidosis

Agenda

Saturday, March 8, 2025, 1:00 pm – 3:00 pm (US ET)

1:00 pm – Welcome and Logistics
1:05 pm – Overview of cardiac amyloidosis
1:30 pm – Radionuclide image acquisition and processing for ATTR cardiac amyloidosis on NaI systems
2:00 pm – Radionuclide image acquisition and processing for ATTR cardiac amyloidosis on CZT systems
2:30 pm – Artifacts and pitfalls, and how to avoid them?
3:00 pm – Final questions

*Credits subject to change

Register Now

This program is supported by an unrestricted educational grant from BridgeBio.