Archive June 2021
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Nuclear Tracers in Left Ventricular Hypertrophy
Pranav Chandrashekar, MD
Ahmad Masri, MD MS
Radionuclide imaging with single photon emission computed tomography (SPECT) or positron emission tomography (PET) is widely used in cardiovascular disease, most commonly in the diagnosis and management of coronary artery disease (CAD), but the unique properties of certain tracers have expanded the utility of these tracers in other applications. The presence of left ventricular hypertrophy (LVH) is common in the general population and can be due to a variety of conditions ranging from hypertension and physiologic hypertrophy secondary to exercise, to other complex conditions such as hypertrophic cardiomyopathy (HCM) and cardiac amyloidosis (CA) [1,2]. LVH is associated with an increased risk of death regardless of the presence of CAD, particularly in those of African descent in whom LVH is more commonly identified [3,4]. Although commonly encountered, the effect of LVH on the performance of radionuclide imaging as well as the use of nuclear tracers in other conditions that present as LVH is not well described. Here we review radionuclide tracers and imaging in LVH.