Archive April 2021
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Myocardial Viability Imaging: An Attractive Idea Without the Clinical Outcomes to Back It Up
Alvin S. Chen, MD
Thomas H. Hauser, MD, MPH, MMSc
Heart failure is increasingly common and presents a major clinical and public health challenge. Coronary artery disease is the leading cause of heart failure in the United States, causing myocardial injury leading to reduced systolic function and ultimately heart failure.1 It was first demonstrated in the 1970s that dysfunctional myocardium in the setting of coronary artery disease could be coaxed back to life using an infusion of epinephrine.2 This dysfunctional myocardium that could regain function was termed viable myocardium. Subsequent studies have shown that coronary revascularization provides more durable improvements in systolic function and superior clinical outcomes.