
Using the Online Submission SystemSubmitting an AbstractImportant Information
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Withdrawing an AbstractIf you want to withdraw an abstract, click on the button at the end of the submission marked "delete submission." Sample AbstractEffect of 3D Iterative Reconstructions of Gated SPECT Perfusion Studies on LV Function and Mass Measurements – Comparisons with Standard Filtered Backprojection Reconstructed Gated SPECT T. Mohmed, E.P. Ficaro, J.N. Kritzman, J.R. Corbett, University of Michigan, Ann Arbor, MI Background: Recently available 3D iterative reconstruction (3D-IR) algorithms permit important time savings during SPECT image acquisitions. The effects of the new 3D-IR methods on the quantification of LV functional parameters are unknown. The purpose of this study was to assess the effect of 3D-IR compared to filtered backprojection (FBP) reconstructions on LV EF, volumes and mass measurements. Methods: Using a new multi-slice SPECT-CT imaging system (SYMBIA-6), 40 patients were studied. All patients were imaged using stress 99Tc- Sestamibi protocol and CT based attenuation correction. 40 subjects (20 male, 20 female) undergoing either pharmacologic or treadmill stress Sestamibi imaging were analyzed. Gated images were acquired on a Symbia T6 SPECT/CT system (Siemens Medical Solutions, Hoffman Estates, IL). Studies were acquired for 30 sec/projection, 180 degree acquisition orbit, 128x128 matrix and 16 frame/cycle cardiac gating. All data were processed and short axis images produced using filtered backprojection and 3D-IR using the 3D FLASH reconstruction algorithm (5 iterations and 8 subsets). FBP images were smoothed using a Butterworth filter (order 5, cut-off 0.35). Iteratively reconstructed data was filtered using a Gaussian 9.6 mm filter. Quantitative results were generated using the commercially available 4DM-SPECT software (INVIA, Ann Arbor, MI). Valve plane placement and LV myocardial contours were verified by an expert user prior to final tabulation of measurements. Results:
Conclusions: Measurements of LV EF, volumes and mass with the 4DM-SPECT quantification algorithms are unaffected by 3D iterative compared to standard FBP SPECT reconstruction algorithms. NotificationAcceptance or non-acceptance of abstracts will be acknowledged by e-mail (please be sure to provide an e-mail address). Notification will be sent to submitting authors in April 2008 (August 2008 for late-breaking clinical trial abstracts) indicating whether or not the abstract has been accepted for programming. The submitting author will be asked to confirm the name and contact information of the presenter, or change it to one of the other authors (in order to comply with the two-abstract presentation limit). Presenting authors who provide verification of trainee status will receive complimentary registration. Presenting authors, who are not trainees, will receive a 50% discount on the early registration fee. Each presenting author will be asked to comply with the ASNC “Disclosure of Faculty Relationships Policy.” Upon abstract acceptance, the presenting author must complete a Disclosure Statement delineating the nature of the relationship and the associated commercial entity. For abstracts that are accepted, titles and co-authors will be listed in the ASNC2008 Final Program available on site at the meeting. Full text of accepted abstracts (except for late-breaking clinical trial abstracts) will be published in the print and online versions of the Journal of Nuclear Cardiology. |